GERD & HIATUS HERNIA
Quick Revision — MUST KNOW
- GERD is reflux of gastric contents into the esophagus producing troublesome symptoms and/or complications.
- The main antireflux barrier consists of the LES, crural diaphragm, intra-abdominal esophagus and angle of His.
- Transient LES relaxations are an important physiological mechanism underlying reflux episodes.
- Hiatal hernia disrupts the normal relationship between the GE junction and diaphragmatic hiatus.
- Hiatal hernia is classified into Types I, II, III and IV.
- Type I = sliding hiatal hernia.
- Types II–IV are paraesophageal hernias.
- GERD may be managed with lifestyle measures, acid suppression and, in selected patients, antireflux surgery.
- Surgical treatment generally involves restoration of the antireflux barrier, often with hiatal repair and fundoplication.
Antireflux Barrier
| Component | Role |
|---|---|
| LES | Physiological high-pressure zone preventing reflux |
| Crural diaphragm | External diaphragmatic component of the antireflux barrier |
| Intra-abdominal esophagus | Positive intra-abdominal pressure helps maintain closure |
| Angle of His | Contributes to the geometry of the gastroesophageal junction |
| Phrenoesophageal membrane | Helps anchor the GE junction at the diaphragmatic hiatus |
Pathophysiology of GERD
- Increased frequency of transient LES relaxations.
- Reduced LES pressure or impaired antireflux barrier.
- Hiatal hernia can impair the normal GE junction–diaphragm relationship.
- Impaired esophageal clearance can increase mucosal exposure to refluxate.
- Delayed gastric emptying may contribute in selected patients.
- Refluxate may contain acid, pepsin, bile and other gastric contents.
Hiatus Hernia — Definition & Classification
A hiatal hernia occurs when abdominal contents, typically part of the stomach, protrude through the esophageal hiatus of the diaphragm.
Clinical Features of GERD
Typical Symptoms
- Heartburn
- Acid regurgitation
- Retrosternal discomfort
- Symptoms after meals
Extraesophageal Associations
- Chronic cough
- Hoarseness
- Throat symptoms
- Asthma association
Alarm Features — When to Investigate
- Dysphagia
- Odynophagia
- Gastrointestinal bleeding
- Unintentional weight loss
- Persistent vomiting
- Anemia or suspected gastrointestinal blood loss
Diagnosis & Investigations
| Investigation | Major role |
|---|---|
| Upper GI endoscopy | Evaluate mucosal injury, erosive esophagitis, Barrett's esophagus, stricture and malignancy. |
| Ambulatory pH monitoring | Objective assessment of pathological acid exposure. |
| pH-impedance monitoring | Detects acid and non-acid reflux and allows symptom association. |
| High-resolution manometry | Evaluates esophageal motility and LES function; important before selected antireflux operations. |
| Barium swallow | Useful for structural assessment, hiatal hernia, strictures and selected postoperative problems. |
Medical Management of GERD
- Lifestyle modification should be individualized.
- Weight reduction is important in patients with overweight or obesity.
- Avoidance of meals close to bedtime can be useful in patients with nocturnal symptoms.
- Proton pump inhibitors (PPIs) are the main pharmacological treatment for acid-mediated GERD.
- H2-receptor antagonists may have a role in selected patients.
- Treatment should be tailored to symptom response, objective findings and complications.
When to Consider Antireflux Surgery
- Objective evidence of GERD with appropriate surgical anatomy.
- Persistent troublesome reflux despite appropriate medical management.
- Patients who are unable or unwilling to continue long-term medical therapy after appropriate evaluation.
- GERD with significant hiatal hernia may require correction of the mechanical defect.
- Severe reflux complications may influence the decision for definitive intervention.
Surgical Treatment of Hiatus Hernia
Surgical repair aims to restore the anatomy of the gastroesophageal junction and reduce the herniated stomach or other abdominal contents.
- Reduction of herniated contents.
- Mobilization of the esophagus and stomach as required.
- Hiatal closure to restore the diaphragmatic hiatus.
- Fundoplication may be added to restore the antireflux barrier.
- Gastropexy may have a role in selected clinical situations.
Mesh in Hiatal Hernia Repair
- Mesh has been studied as an adjunct to hiatal closure, particularly in larger hernias.
- Evidence regarding routine mesh use remains uncertain.
- Potential benefits must be balanced against mesh-related complications.
- Mesh choice and placement should be individualized according to anatomy, tissue quality and surgeon experience.
Fundoplication
| Procedure | Basic concept |
|---|---|
| Nissen | Complete 360° fundoplication. |
| Toupet | Posterior partial fundoplication. |
| Dor | Anterior partial fundoplication. |
Complications of Antireflux Surgery
- Postoperative dysphagia
- Gas-bloat syndrome
- Inability to belch or vomit
- Recurrent reflux
- Wrap migration or disruption
- Recurrent hiatal hernia
- Slipped or misplaced wrap
Paraesophageal Hernia — Clinical Features
- May be asymptomatic and discovered incidentally.
- Can cause dysphagia and postprandial discomfort.
- Early satiety may occur.
- Reflux symptoms may coexist.
- Large hernias can produce respiratory symptoms through thoracic compression.
- Complications include obstruction, incarceration, strangulation and gastric volvulus.
Hiatal Hernia — NEET SS Comparison
| Type | GE Junction | Stomach | Key Point |
|---|---|---|---|
| I | Above hiatus | Usually slides upward | Sliding hernia |
| II | Normal position | Fundus herniates | True paraesophageal |
| III | Above hiatus | Herniates | Mixed type |
| IV | Usually displaced | Stomach + another organ | Complex paraesophageal hernia |
NEET SS — Facts You Should Never Miss
- GERD results from failure of the antireflux barrier.
- LES is a major component of the antireflux barrier.
- Crural diaphragm contributes to the gastroesophageal antireflux mechanism.
- Transient LES relaxations are an important mechanism of reflux.
- Type I hiatal hernia = sliding hernia.
- Type II = true paraesophageal hernia.
- Type III = mixed sliding + paraesophageal component.
- Type IV = stomach plus another abdominal organ herniates.
- Endoscopy evaluates mucosal disease and complications.
- Reflux monitoring provides objective evidence when GERD remains uncertain.
- Manometry is important when evaluating esophageal motility and before selected antireflux operations.
- Hiatal hernia repair restores the anatomy of the GE junction and diaphragmatic hiatus.
- Fundoplication may be added to restore the antireflux barrier.
- Current evidence does not support a universal recommendation for routine mesh use in hiatal hernia repair.
NEET SS Clinical Approach
GERD + Typical Symptoms
Assess symptoms, alarm features, response to treatment and need for objective testing.
GERD + Dysphagia
Think structural disease or motility disorder and investigate appropriately.
GERD + Large Hiatal Hernia
Evaluate the anatomy and consider whether definitive mechanical correction is appropriate.
Paraesophageal Hernia + Acute Symptoms
Consider obstruction, volvulus, incarceration or ischemia.
Frequently Asked Questions
Test Your Knowledge
25 NEET SS-level MCQs on GERD & Hiatus Hernia