AMC Statistics

Which one of the following is the study of choice for determining the state of vitamin B12 deficiency in Australia?

A) Cohort study.
B) Case-control study.
C) Randomized controlled trial (RCT).
D) Cross-sectional study.
E) Case series.

D) Cross-sectional study

  • A cross-sectional study is the study of choice when assessing the prevalence of a condition or health-related state — such as vitamin B2  deficiency — in a specific population at a particular point in time.

  • In Australia, if the goal is to determine how widespread vitamin D deficiency is, a cross-sectional design provides a snapshot, allowing for analysis of:

    • Population characteristics (age, gender, region, season)

    • Risk factors (e.g., sun exposure, diet)

    • Correlation with serum vitamin D levels


Why other options are not correct:

  • A) Cohort study – Good for studying incidence and identifying risk factors over time, but not ideal for assessing current prevalence.

  • B) Case-control study – Used to examine associations between exposures and rare diseases, not to measure prevalence.

  • C) Randomized controlled trial (RCT) – Best for evaluating interventions (e.g., vitamin D supplementation), not for measuring deficiency in a population.

  • E) Case series – Descriptive and involves a small group of individuals with a condition; cannot determine population-level prevalence.

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