colon

CEA

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True regarding CEA is 

  1. Low specificity
  2. Falls after 1 week of surgery to baseline
  3. Preoperative high value is good prognostic marker
  4. Follow up, first test of CEA in 8-10 days followed by weekly tests thereafter

Answer after Q 20

Crohn Extraintestinal manifestations

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Q) Extra intestinal manifestation of Ulcerative Colitis  not cured by surgery

a) PSC

b) Sacro ileitis

c) Episcleritis

d) Erythema nodosum

Questions on colon 21-30

Ans ) a PSC 

Arthritis,  ankylosing  spondylitis,  erythema  nodosum,  and  pyoderma  gangrenosum  typically  improve  or  completely  resolve after  colectomy.

PSC  occurs  in  5%  to  8%  of  patients  with  ulcerative  colitis. 

HLA-B8  or HLA-DR3  haplotype  are  10  times  more  likely  to  develop  PSC. 

The  risk  for  colon  cancer   in these  patients  is  up  to  five  times  greater   than  in  patients  with ulcerative  colitis  alone.  These  tumors  are  more  likely  to  arise proximal  to  the  splenic  flexure . Colectomy  has  no  effect  on  the course  of  PSC.

 

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Poor Prognosis in colon polyp

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Q) All are poor prognostic factors in colonic polyp except?

a) Poorly diff in the head

b) Moderately differentiated polyp

c)  Involving the stalk

d) Margins positive

Answer

Poor prognostic factors in a polyp aare

1. histologically  poorly  differentiated invasive  carcinoma

2. cancer  cells  observed  in  the lymphovascular  spaces,  there  is  a  more  than  a  10%.......... 

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