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Q1. A 60-year-old female presents with alkaline reflux gastritis after Billroth I gastrectomy. What is the ideal management?
Answer
Answer: b
Explanation: Roux-en-Y is preferred to prevent bile reflux. A Roux limb (~60 cm) reduces symptoms like epigastric pain, bilious vomiting, and weight loss. HIDA scan can confirm diagnosis.
Ref: Sabiston, SKF
b) Roux-en-Y gastrojejunostomy
Teaching Points:
- Roux-en-Y gastrojejunostomy: Diverts bile and pancreatic secretions away from stomach remnant, relieving symptoms. Gold standard for severe symptomatic cases.
- Conversion to Billroth II: Gastrojejunostomy without Roux limb; bile reflux often persists or worsens.
- Total gastrectomy: Reserved for refractory cases or malignancy; high morbidity if stomach remnant is otherwise healthy.
- Conservative management: PPIs, sucralfate, prokinetics may temporarily relieve symptoms but do not treat underlying bile reflux.
Take-Home Points:
- Alkaline reflux gastritis occurs due to reflux of duodenal contents into stomach remnant post-gastrectomy.
- Symptoms: epigastric pain, nausea, vomiting, weight loss; Endoscopy shows bile pooling and mucosal inflammation.
- Definitive treatment: Roux-en-Y gastrojejunostomy.
- Conservative treatment is only for mild symptoms or temporary relief.
- Conversion to Billroth II may worsen reflux and should be avoided.
Q2. A 58-year-old male with Type I bleeding gastric ulcer unresponsive to endoscopy. Best treatment?
Answer
c) Distal gastrectomy
Teaching Points:
- Type I gastric ulcer: Located on the lesser curvature (body/antrum).
- Endoscopic failure: Persistent bleeding requires surgery.
- Wedge resection: Not suitable for lesser curvature ulcers; may compromise blood supply.
- Oversewing the vessel: Only temporary hemostasis; high risk of recurrence.
- Distal gastrectomy: Removes ulcer completely; first-line surgical option for Type I ulcers.
- Distal gastrectomy with vagotomy: Reserved for recurrent ulcers or high acid states; not routine for first-time bleeding Type I ulcer.
Take-Home Points:
- Surgery is indicated for bleeding gastric ulcers unresponsive to endoscopic therapy.
- Type I ulcers (lesser curvature) → distal gastrectomy is preferred.
- Wedge resection or oversewing is insufficient for preventing recurrence.
- Vagotomy is not routinely required unless there is a history of recurrent or acid-related ulcers.
Q3. Which statement is NOT true about H. pylori?
Answer
Teaching Points:
- H. pylori is a gram-negative, microaerophilic, spiral-shaped bacterium.
- Transmitted mainly by person-to-person (oral–oral or fecal–oral) routes.
- Infection is common in developing countries and low socioeconomic groups.
- Prevalence is low in developed nations due to improved hygiene.
Take-Home Points:
- H. pylori → Gram-negative, microaerophilic organism causing chronic gastritis and peptic ulcer disease.
- Transmission: Person-to-person.
- Common in developing, low socioeconomic populations.
- “Highest infectivity in developed world” is incorrect.
Q4. Which hormone is NOT released in the duodenum?
Answer
d) Peptide YY
Teaching Points:
- Gastrin: Secreted by G cells in antrum and duodenum; stimulates acid secretion.
- Motilin: Secreted by M cells in duodenum and jejunum; increases GI motility.
- Somatostatin: Secreted by D cells in stomach, duodenum, and pancreas; inhibits other GI hormones.
- Peptide YY: Secreted by L cells in ileum and colon; not secreted in duodenum.
Take-Home Points:
- Duodenal hormones: Gastrin, CCK, Secretin, Motilin, Somatostatin.
- Peptide YY → released from ileum and colon (distal gut).
- PYY slows gastric emptying and inhibits pancreatic secretion.
- Understanding secretion sites helps in GI physiology and surgery exams.
Q5. What is the treatment for bleeding duodenal diverticulum?
Answer
a) Diverticulectomy
Teaching Points:
- Bleeding duodenal diverticulum → rare cause of upper GI bleeding.
- Initial management: Endoscopic or angiographic control.
- Persistent/recurrent bleeding → surgical intervention required.
- Diverticulectomy is the definitive surgical treatment.
- Diverticulization is indicated in perforation, not in bleeding.
- Diverticulopexy and subtotal diverticulectomy are not standard for bleeding control.
Take-Home Points:
- Bleeding duodenal diverticulum → treat endoscopically first; surgery if uncontrolled.
- Diverticulectomy with primary duodenal closure is preferred.
- Ensure duodenal repair integrity and drainage postoperatively.
- Diverticulization reserved for duodenal perforations, not bleeding.