New NEET Pattern

Giant cell tumor femur

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Q) A 22-year-old woman presents with a giant cell tumor (GCT) of the distal femur. Appropriate treatment would be:

A. Curettage and debridement
B. Amputation
C. Radiation
D. Preoperative chemotherapy, resection, and adjuvant chemotherapy
🚫 This answer is available only for Premium Members. Join Premium Surgery Course to view explanations.

MCQ on General onco

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MCQ on Mechanisms of Cancer Cells Invasion
Q) Which is not a mechanism of cancer cells invasion?
✅ Answer: D. Extracellular matrix dissolution is due to physical factors

🔍 Explanation:
Cancer cells secrete collagenases and proteases that chemically dissolve extracellular boundaries to facilitate invasion.
The three main mechanisms by which cancer cells invade are:
- **Dissolution of Extracellular Matrix**: Cancer cells secrete enzymes like matrix metalloproteinases (MMPs) that break down the extracellular matrix, allowing for tissue penetration.
- **Acquisition of Mobility**: Cancer cells undergo changes in their adhesion properties and cytoskeleton, which allows them to move through tissues.
- **Rise in Interstitial Pressure**: Although this may affect fluid dynamics, it is a consequence of tumor growth, not a direct invasion mechanism.

🧠 Key Point: The dissolution of the extracellular matrix is a chemical process, not due to physical factors like pressure.

PET CT In Urological Malignancies

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Q) PET CT in urological  malignancies most useful in? ( Questions as per NEW NEET SS Pattern) 

a) RCC

b) Testis

c) Urinary bladder

d) all

Ans B

Testis

In men with testis cancer, it is recommended in the follow-up of patients with seminoma with any residual mass

Promising in Urinary bladder ca

Not used in RCC 

BAiley page 1391

Stemmer’s test

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Q) Stemmer Test is done in

a) Lymphedema

b) Deep Venous Thrombosis

c) Superficial Venous thrombosis

d) Factitious lymphedema