Sarcoma

Giant cell tumor femur

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Q) A 22-year-old woman presents with a giant cell tumor (GCT) of the distal femur. Appropriate treatment would be:

A. Curettage and debridement
B. Amputation
C. Radiation
D. Preoperative chemotherapy, resection, and adjuvant chemotherapy
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Sarcoma with early lymph node spread

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Soft Tissue Sarcoma MCQ – Early Lymph Node Metastasis – NEET SS
Q) Soft tissue sarcoma with early lymph node metastasis is:
✅ Correct Answer: d) All of the above

🔍 Explanation:
- Most soft tissue sarcomas spread hematogenously.
- However, certain sarcomas are known for early lymph node metastasis including:
✅ **Angiosarcoma** – High lymphatic spread
✅ **Pleomorphic sarcoma** (Undifferentiated pleomorphic sarcoma, formerly MFH)
✅ **Epithelioid sarcoma, rhabdomyosarcoma, clear cell sarcoma** – also associated with LN spread

📚 Early LN spread is a known exception pattern in STS and has prognostic implications.

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