Metastatic NET

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Q) Girl with pain upper abdomen.  CT Abdomen shows  4 X 5 cm mass in segment V  and thickening in ileocecal region. Liver Biopsy shows NET. Next line of management:?

Immunosuppression

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Q) False regarding immunosuppresant medicines ?

a. MMF is a reversible inhibitor of IMD-DH
b. Both Cyclosporine  and tacrolimus inhibit NF-KB and its downstream effects
c. Everolimus acts on FKBP12To inhibit Calcineurin activity
d. ALG are more used in pancreas transplant

Ectopic pancreas

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Q) Not a site of ectopic pancreas
a. Esophagus
b. GB
c. Liver
d. Jejunum

Loss of cell Surface antigen

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Q) Loss of cell surface antigen is a feature of 
A. CIS
B. NO RELATION WITH GRADE
C. LOW GRADE TUMOR
D. HIGH GRADE TUMOR

Ans d High grade

The ABO(H) blood group system consists of terminal oligosaccharide antigens carried by glycoproteins or glycolipids in hematopoietic or epithelial cells 

Their biosynthesis is presumed to be controlled by the ABO(H), Se, H, Le, and X blood group genes .

These antigens are present on normal bladder epithelium of secretor individuals but not on some low-grade and early-stage papillary urothelial carcinomas 

Moreover, initially expressing tumours lose these cell surface antigens upon local recurrence, progression to invasion or metastization 

D 2 gastrectomy

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Q) D2 gastrectomy false statement is ? ( AIIMS 2021) 
a. No benefit in Overall Survival ( OS) 

b. Better Disease free Survival ( DFS) 
c. Recommended to take stomach, omentum, retro peritoneum en masse
d. Can remove spleen or pancreas if involved