Q) 47 year old premenopausal lady with a 3X 3cm left breast lump with IDC grade III, TNBC.
On examination, there is a single subcentimetric mobile soft mobile ipsilateral axillary LN palpable. Usg nodes no loss of hilum. Management of axilla?
a) SLND
b) ALND
c) Radiotherapy only
d) No treatment
Ans a
Selective lymph node dissection
ACOSOG Z0011 trial 0 (stages I and II) in patients who undergo breast conservation therapy, axillary lymph node dissection does not improve locoregional control or survival.
This trial has demonstrated the safety of limiting axillary surgery to the SLNB without performing formal axillary dissection for sentinel node positivity.
This avoids of the morbidity of the axillary dissection.
If node is positive the patient should receive adjuvant chemotherapy and radiation therapy.
Q ) Hereditary diffuse Gastric carcinoma is associated with which breast cancer A. Ductal carcinoma NOS subtype B. Lobular carcinoma C. DCIS D. Metaplastic carcinoma
Q) IN RTOG trial for ductal carcinoma in situ (DCIS) favourable tumor was defined as
a) <3,5 cm in size and 2mm free resection margin
b) <2.5 cm and 2mm margin
c) <3 cm size and 3 mm margin
d) <2.5 cm size and 3 mm margin
Answer - Free answers to surgery mcqs
d
Ductal carcinoma in situ is a pre invasive state in which the cancer cells have not breached the epithelial membrane. It can develop into cancer in 20%.
Simple mastectomy is the standard of care but many centers now consider it over treatment.
Van Nuys system uses
Age of the patient
type of DCIS
presence of microcalcification
Size
resection margin
On mammography this is seen as clustered clustered calcification
Treatment options are
Mastectomy
Breast conserving therapy (Lumpectomy +radiation and hormonal)
More recently, Eastern Cooperative Oncology Group investigators reported the frst result of a relatively large prospective single-arm study of surgery with negative margins of at least 3 mm without radiation therapy for patients with favorable subsets of DCIS.
Patients with low-grade or intermediate-grade DCIS measuring 2.5 cm or smaller had a 5-year rate of ipsilateral breast recurrence of only 6.1%. In contrast, patients with high-grade disease had a much higher 5-year ipsilateral breast recurrence rate of 15.3%.
Q) In terms of cure best results in inflammatory carcinoma breast are seen with-
a) Surgery alone
b) Chemotherapy
c) Radiotherapy
d) All of the above
Ans wer
d)
Inflammatory carcinoma of the breast is a rare aggressive tumor that blocks the sub dermal lymphatics as a result of which cutaneous edema is common . Differentiating it from a breast abscess is important and biopsy is diagnostic. It is also responsible to peau d orange
Treatment is multidisciplinary and involves, chemotherapy followed by surgery followed by radiotherapy.
Rapid unilateral development of inversion of nipple is a dangerous sign and warrants further diagnosis. Further circumferential retraction is also sign of carcinoma.
Simple nipple inversion occurring at puberty or retracted nipple is of unknown cause and is bilateral in 25%. Mostly No treatment is required for this and condition resolves spontaneously during pregnancy and lactation.
Suction pumps and cosmetic surgery can also help.
Inversion of nipple associated with malignancy may be with or without the presence of lump. Associated discharge from the nipple can point to the diagnosis.
Duct ectasia - slit like retraction of nipple . ALso seen in duct ectasia is green, black or blood stained discharge from nipple
Ref - Bailey 801
Grading of benign nipple inversions for management
In grade I, the nipple is easily pulled out manually and maintains its projection quite well. It has minimal fibrosis thus, manual traction and a single, buried purse-string suture are enough for the correction.
Grade II (majority) the nipples can be pulled out but cannot maintain projection and tend to go back again. These nipples are thought to have moderate fibrosis beneath the nipple.
In grade III, to which the least number of inverted-nipple cases belong, the nipple can hardly be pulled out manually. Severe fibrosis made it impossible to reach optimal release of the fibrotic band with the preservation of the ducts.
Q) Popcorn calcification in breast is seen in which condition
a) Fibroadenoma
b) Periductal fibrosis
c) Carcinoma breast
d) Duct ectasia
Free answer to Surgery MCQs
a
Calcifications associated with fibroadenomas have been termed popcorn calcifications because of their large size and dense, coarse appearance. Calcifications in fibroadenomas usually begin at the periphery and then involve the central portion of the fibroadenoma.