Jejunum

Small Bowel NET

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Q) 45 year old male with 2 cm Jejunal Neuroendocrine tumor ( NET).

Dota Scan Shows no metastasis What would be the best management in him?

a) Octreotide

b) Resection & Anastomoses of jejunum

c) Resection and Anastomoses with mesenteric excision

d) Radiotherapy

 

Small Bowel Adenocarcinoma & its Risk Factors

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Small Bowel Adenocarcinoma MCQ
Q) Which of the following is not a risk factor / least associated with small bowel adenocarcinoma?
a) Familial adenomatous polyposis (FAP)
b) Hereditary nonpolyposis colorectal cancer
c) Peutz-Jeghers syndrome
d) Juvenile polyposis coli
Correct Answer: d) Juvenile polyposis coli
Explanation: Juvenile Polyposis Coli is least associated with small bowel adenocarcinoma. Risk factors for Small Bowel Adenocarcinoma: 1. Hereditary polyps: - Familial adenomatous polyposis (FAP) - Hereditary nonpolyposis colorectal cancer - Peutz-Jeghers syndrome 2. Inflammatory and metabolic: - Crohn disease - Gluten-sensitive enteropathy (celiac sprue) - Prior peptic ulcer disease - Cystic fibrosis - Biliary diversion (e.g., previous cholecystectomy) 3. Lifestyle: - Smoking - Heavy alcohol use (>80 g/day ethanol) - Red meat/salted food intake 4. Genetic: - Kras - 5q (APC gene) - 17q (p53 gene) - 18q - DPC4 - SMAD4 - MSI-H (Microsatellite Instability-High)
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