Small Bowel Adenocarcinoma & its Risk Factors

Small Bowel Adenocarcinoma MCQ
Q) Which of the following is not a risk factor / least associated with small bowel adenocarcinoma?
a) Familial adenomatous polyposis (FAP)
b) Hereditary nonpolyposis colorectal cancer
c) Peutz-Jeghers syndrome
d) Juvenile polyposis coli
Correct Answer: d) Juvenile polyposis coli
Explanation: Juvenile Polyposis Coli is least associated with small bowel adenocarcinoma. Risk factors for Small Bowel Adenocarcinoma: 1. Hereditary polyps: - Familial adenomatous polyposis (FAP) - Hereditary nonpolyposis colorectal cancer - Peutz-Jeghers syndrome 2. Inflammatory and metabolic: - Crohn disease - Gluten-sensitive enteropathy (celiac sprue) - Prior peptic ulcer disease - Cystic fibrosis - Biliary diversion (e.g., previous cholecystectomy) 3. Lifestyle: - Smoking - Heavy alcohol use (>80 g/day ethanol) - Red meat/salted food intake 4. Genetic: - Kras - 5q (APC gene) - 17q (p53 gene) - 18q - DPC4 - SMAD4 - MSI-H (Microsatellite Instability-High)

Type of statistical errors

Q) A Surgical thesis was completed but later found to have Type II  error. This means ?

a) Benefit is perceived when really there is none (false positive).

b) Benefit is missed when it was there to be found (false negative).

c) Sample size was wrong

d) None of the above

Nylon suture

Q) Nylon is now commonly  used in abdominal wall closure. It is made of ?

a) Polyamide

b) Polyester

c) Nickel

d) Polybutylene

 

 

Stem cells

Autologous Cells in Tissue Engineering MCQ | NEET SS Surgery
Surgery MCQ · Tissue Engineering

Autologous cell used in tissue engineering is:

A) Somatic cells
B) Fetal cells
C) HESC (human embryonic stem cells)
D) All
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Tissue Engineering and Stem Cells: NEET SS Surgery Preparation

Tissue engineering is an interdisciplinary field that combines cells, biomaterial scaffolds and biological signals to repair, replace or regenerate damaged tissues. It has applications in regenerative medicine, reconstructive surgery, wound healing and the development of bioengineered tissues.

Stem cell biology is an important topic in surgical entrance examinations. Questions may explore stem cell classification, differentiation, sources of cells, scaffold materials, cellular interactions and the principles underlying tissue regeneration.

Understanding the terminology used in cell-based therapies is essential for distinguishing different cell sources and their potential clinical applications. These concepts also help explain issues related to immune compatibility, cell availability, safety and the translation of laboratory research into clinical practice.

Topics to Revise

  • Principles and applications of tissue engineering
  • Stem cell classification and differentiation potential
  • Cell sources used in regenerative medicine
  • Biomaterial scaffolds and tissue regeneration
  • Clinical applications and limitations of cell-based therapies

Attempt the MCQ above before reviewing the answer. Regular practice with concept-based questions can help reinforce basic science principles relevant to NEET SS Surgery and other superspeciality entrance examinations.

Perio OP Management Chronic Kidney disease

Q) 45 year old male is on chronic dialysis for MGN. He is due to undergo Right colonic resection for ca caecum. Which of the following parameters will be of least worry to the anesthetists due to chronic kidney disease?

a) Cardiac

b) Fluid and electrolyte

c) Coagulational

d) Pulmonary

Peri Op management MCQs

 

Virchow’s triad

Virchow's Triad MCQ
Q) Which of the following does not form a part of Virchow's triad?
a) Endothelial damage
b) Slow blood flow
c) Platelet defects
d) Hypercoagulable state
Correct Answer: c) Platelet defects
Explanation: Virchow triad (venous stasis, endothelial injury, and hypercoagulability) describes the factors contributing to venous clot formation and thromboembolism. Platelet defects are associated with arterial thrombosis and not venous. Virchow is known as "the father of modern pathology" and founder of social medicine. --- Virchow’s Triad: Unraveling the Factors Behind Thrombosis 1. Endothelial Damage: Endothelial cells line blood vessels. When injured, they expose tissue factor, initiating clot formation. Seen in atherosclerosis, sepsis, trauma. 2. Abnormal Blood Flow: Stasis or turbulence promotes clotting. Causes include prolonged immobilization, atrial fibrillation, varicose veins. 3. Hypercoagulability: A state of increased clotting tendency. Causes: • Oral contraceptives, obesity, pregnancy • Inherited mutations (e.g. factor V Leiden) • Smoking, malignancy Most thrombi result from a combination of the above factors. Recognizing the triad aids in prevention and diagnosis of thromboembolic disease.