Splenectomy

Q) Which of the following is not an indication for splenectomy in Non Hodgkin Lymphoma?
 
a)  Massive splenomegaly
b) Signs of hypersplenism
c) Diagnosing and staging of isolated splenic disease

d) All are indications for splenectomy

The correct answer is: d) All are indications for splenectomy

Explanation:

In Non-Hodgkin Lymphoma (NHL), splenectomy may be considered in the following scenarios:

  • Massive splenomegaly causing symptoms or complications like infarction, pain, or risk of rupture.

  • Hypersplenism, which leads to cytopenias (low counts of blood cells) that are not responsive to medical therapy.

  • Diagnostic and staging purposes, especially in isolated splenic disease where biopsy is inconclusive or not feasible.

 

Radiation proctitis

Radiation Proctitis Surgery Indications MCQ | NEET SS Surgery
Q) In radiation proctitis surgery is needed in all except
a) Pain Abdomen
b) Rectal stricture
c) Haemorrhage
d) Vesical Fistula

Answer: a) Pain Abdomen

In radiation proctitis, surgery is typically indicated for complications that are severe or unmanageable through conservative measures.

A) Pain Abdomen: While abdominal pain can be a symptom associated with radiation proctitis, it is not an indication for surgery on its own. Pain management and other conservative treatments can be employed first.

B) Rectal stricture: This can cause significant obstruction and may require surgical intervention to restore normal bowel function.

C) Haemorrhage: Severe bleeding may necessitate surgical intervention if not controlled by endoscopic or conservative measures.

D) Vesical Fistula: A serious complication that often requires surgical repair.


Classification:

  • Acute: Within 6 months of starting radiation
  • Chronic: After 6 months (usually 8–12 months post therapy)

Radiation Proctitis Severity (RTOG):

  • Grade 1: Mild, self-limiting
  • Grade 2: Conservative management required
  • Grade 3: Severe, affects lifestyle
  • Grade 4: Life-threatening → Surgery needed

Prevention:

  • Conformal radiation techniques
  • Amifostine (free radical scavenger)
  • Sucralfate not beneficial in trials

Treatment:

Medical:

  • Butyrates
  • 5-ASA
  • Sucralfate
  • Metronidazole
  • Short chain fatty acids
  • Topical formalin
  • Hyperbaric oxygen

Endoscopic:

  • Dilatation
  • Heater probe / bipolar cautery
  • Nd:YAG laser
  • APC
  • RFA

Surgery:

  • Diverting ostomy – for stricture/incontinence
  • Flap reconstruction – gracilis/Martius flap for fistula
  • Proctectomy – severe fistula, pain, intractable bleeding

Amoebic Liver abscess

Q) Not true about amoebic liver abscess

a) Most common liver enzyme elevated is ALT
b) Metronidazole and luminal amebicide needed in all cases
c) In peritonitis due to amoebiasis perforation of colon are less than perforation of liver
d) 5% to 15% of patients with ALA may be resistant to metronidazole

 

Answer
The cecum is the most common site of amebic colitis, and the right lobe of the liver is more commonly affected because of drainage
of the right portal branch from the right side of the colon. The condition usually starts as diffuse amebic hepatitis; liver cells
undergo liquefactive necrosis

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GIST Stomach

Q ) Antral GIST 1cm incidentally found on UGIE. True regarding its management

a) Surgical resection resection of GIST (More questions on GIST here) 

b) Endoscopic resection

c) Resection required if EUS suggests irregular border with cystic spaces

d) Endoscopic surveillance, if size >2cm then resect

Answer ( You need to be a premium member to see this) 

GIST are usually found in the stomach (40% to 60%), small intestine (30%), and colon (15%). Clinically they appear  in patients older than 50 years.

They generally have an equal male-to-female ratio or a slight male predominance.

They are rarely associated with familial syndromes such as GISTparaganglioma syndrome (Carney triad), neurofibromatosis 1, and von Hippel-Lindau disease, but most develop de novo. 

natural history breast cancer

Q. True about breast cancer is?

a) Doubling time of breast tumor is 1 month

b) Skip metastasis in level iii lymph nodes is common

c) Lungs are commonly involved by direct invasion

d) Dimpling of skin is due to shortening of cooper's ligaments

Ans