Q) CDH 1 gene is associated with which cancer
a) Breast
b) Colon
c) Prostate
d) Renal
Gene mutation associated with CDH
E Cadherin is involved in
a) Cell Adhesion
b) Cell maturation
c) Managing intracellular chemical signals
d) It acts as a tumor suppressor protein
Q) Origin of prostatic carcinoma is from which zone
A. Transition zone
B. Peripheral zone
C. Central zone
D. AMS
Q) Poor prognostic feature for NSGCT (Non Seminomatous germ cell tumor)
A. Age more than 40 years
B. Mediastinal tumour
C. AFP level less than 10,000
D. Non Pulmonary visceral metastasis absent
Q ) Which of the following statement regarding yttrium 90 is incorrect: ( From Gen onco Surgery Q 21-40)
a. Used for brachytherapy
b. Is a pure beta emitter with range of 1 cm
c. Most commonly used for treatment of ca prostate
d. Used in treatment of both primary and metastatic liver cancer through hepatic artery embolization
Q) CA rectum 5 cm from anal verge which is T1N0 on evaluation. which of the following cannot be done for the treatment of the patient
A. Inter sphincteric resection
B. APR
C. Trans anal endoscopic resection
D. LAR
Q ) Cancer susceptibility syndrome caused by activation of proto-oncogene are all except- ( Question from Gen onco section)
a) Hereditary papillary renal cancer
b) MEN1
c) Familial melanoma
d) Costello syndrome
Q) Carcinoma Penis invading into the Corpora Spongiosum is ?
a) T1a
b) T1b
c) T2
d) T3
Q) GNRH agonist is
A. Buserelin
B. Anastrazole,
C. Exemestane,
D. letrozole
