Carbon Monoxide poisoning

Q. Carbon monoxide poisoning true is 

a)  It is having 10 times more affinity than oxygen
b) 60 percent is not deadly.
c) . Concentration above 10% are dangerous and need observation
d)  Concentration above 10% are dangerous and need treatment with pure oxygen for more than 24 hours

d

Option A: Affinity of CO for Hb is 200-250 times that of oxygen. It causes a conformational change in Hb molecule and reduces affinity of Hb for O2, shifting the oxyhemoglobin dissociation curve to the left.

Option B: Concentrations less than 10% are usually asymptomatic. Concentrations >60% are fatal. Arterial carboxyhemoglobin level must be obtained because pulse oximetry can be falsely elevated.

Option C: Concentrations above 10 per cent are dangerous and need treatment with pure oxygen for more than 24 hours. Administration of 100% O2 reduces the half-life of CO from 250 minutes in room air to 40 to 60 minutes on 100% oxygen.

Timing after esophagus perforation

Delayed Esophageal Perforation MCQ | mcqsurgery.com
Q) A 40-year-old man presents 4 days after severe vomiting with chest pain, fever, and breathlessness. On examination, his pulse is 110/min and blood pressure is 110/80 mmHg. Chest X-ray and CT scan show a left-sided pleural effusion with mediastinal air, suggestive of an esophageal perforation diagnosed approximately 96 hours after onset. What is the best management option?
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Fibrolamellar carcinoma of the liver

Fibrolamellar Carcinoma Liver MCQ |

Fibrolamellar Carcinoma Liver MCQ – Young Female Liver Tumor

📘 Theme: Liver Tumors – Hepatobiliary Surgery (NEET SS / INI-CET High Yield)

Fibrolamellar Carcinoma MCQ

Which of the following statements regarding fibrolamellar carcinoma of the liver is correct?

A. Occurs in the setting of cirrhosis
B. Has worse survival than hepatocellular carcinoma
C. Can be followed up for long time
D. Seen in young females

Answer: D. Seen in young females

Explanation

Fibrolamellar carcinoma (FLC) is a rare variant of hepatocellular carcinoma that typically affects adolescents and young adults, often females, without underlying cirrhosis or chronic liver disease. Unlike conventional HCC, AFP is usually normal or only mildly elevated.

Histologically, it is characterized by large eosinophilic tumor cells separated by dense lamellar fibrosis.

Why other options are incorrect

  • Occurs in the setting of cirrhosis: False. FLC usually arises in non-cirrhotic livers.
  • Has worse survival than hepatocellular carcinoma: False. Fibrolamellar carcinoma generally has better survival than conventional HCC because patients are younger and liver function is preserved.
  • Can be followed up for long time: False. Surgical resection is the treatment of choice because the tumor has malignant potential.

High-yield teaching points

  • Young patient + liver mass + no cirrhosis = think fibrolamellar carcinoma.
  • AFP is often normal in fibrolamellar carcinoma.
  • Central scar may mimic focal nodular hyperplasia on imaging.
  • Best treatment is aggressive surgical resection.

Practice More Surgery MCQs

Compartment syndrome of limb

Compartment Syndrome of Limb – Free Surgery MCQ

Q) All are true about compartment syndrome of limb except?

a) Diagnosis is unlikely if pulse is felt distally
b) There is pain on passive stretching of the limb
c) Pain is out of proportion to the signs
d) Muscles of calf and forearm are commonly involved

Examination of cranial nerves in head injury

Q) Gaze paresis is seen after head injury? What is responsible for this

a) Facial nerve injury

b) Vestibulo cochlear nerve injury

c) Brain stem dysfunction

d) Optic nerve injury

 

Gaze paresis is inability to produce horizontal eye movements in one or both directions. Examination of cranial nerves in head injury is very important to fully assess the extent of injury.

Q Which of the following is not a criteria for diagnosing Sphincter of Oddi Dysfunction

a) Common Bile Duct  diameter more than 12 mm on USG

b) Decrease in Common Bile Duct  pressure after infusion of Cholecystokinin

c) Ampullary pressure more than 40 mm Hg

d) Delayed emptying of contrast from Common Bile Duct after ERCP

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