Sarcoma with early lymph node spread

Soft Tissue Sarcoma MCQ – Early Lymph Node Metastasis – NEET SS
Q) Soft tissue sarcoma with early lymph node metastasis is:
Correct Answer: d) All of the above

🔍 Explanation:
- Most soft tissue sarcomas spread hematogenously.
- However, certain sarcomas are known for early lymph node metastasis including:
✅ **Angiosarcoma** – High lymphatic spread
✅ **Pleomorphic sarcoma** (Undifferentiated pleomorphic sarcoma, formerly MFH)
✅ **Epithelioid sarcoma, rhabdomyosarcoma, clear cell sarcoma** – also associated with LN spread

📚 Early LN spread is a known exception pattern in STS and has prognostic implications.

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Fibrolamellar HCC

Fibrolamellar HCC MCQ – Liver Tumors – NEET SS Surgery
Q) Fibrolamellar HCC is associated with? ( #NEET Onco Questions 2020)
Correct Answer: a) Young age

🔍 Explanation:
- Fibrolamellar Hepatocellular Carcinoma typically affects younger patients without underlying cirrhosis.
- It is often well-demarcated, encapsulated, and contains a central fibrotic scar.
- Prognosis is better than classic HCC due to higher resectability, absence of chronic liver disease, and a more indolent behavior.
- Long-term survival can be expected in ~50–75% of patients.
- However, lymph node metastasis **can occur**, and when present, is associated with poorer outcomes.

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