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Bevacizumab

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Bevacizumab MCQ
Q) Not true about use of Bevacizumab
a) It is a humanized monoclonal antibody against VEGF A
b) Bevacizumab is a first-line treatment in metastatic nonsquamous non-small cell lung cancer.
c) Bevacizumab is a first-line or second-line therapy for metastatic colorectal cancer
d) Its major advantage is that it has replaced combination chemotherapy
Correct Answer: d) Its major advantage is that it has replaced combination chemotherapy
Explanation: a) True – Bevacizumab is a humanized monoclonal antibody targeting vascular endothelial growth factor A (VEGF-A), thereby inhibiting angiogenesis. b) True – Bevacizumab is used as first-line treatment in combination with chemotherapy for metastatic nonsquamous non-small cell lung cancer (NSCLC). c) True – Bevacizumab is used as first-line and second-line therapy in combination with chemotherapy for metastatic colorectal cancer. d) Not true – Bevacizumab is not a replacement for combination chemotherapy. Instead, it is used in combination with standard chemotherapy regimens to improve efficacy. It is not used as a monotherapy in most settings.

Perioperative steroid management in IBD

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Q) All are true  regarding perioperative management Of IBD on steroid except

a) Minor procedure needs only routine steroidal dose supplementation
b) Major procedures  needs Hydrocort 100-150 mg tds
3.Chronic steroid use causing adrenal failure that  presents with hypotension, vomiting, fever, lethargy
4.All cases of UC need supraphysiological dose of steroid.

Maltoma Stomach

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Gastric MALT Lymphoma MCQ | mcqsurgery.com
Q) A 55-year-old man presents with dyspepsia and weight loss. Upper GI endoscopy shows multiple erosions in the antrum. Biopsy reveals a low-grade B-cell lymphoma arising from mucosa-associated lymphoid tissue. Helicobacter pylori is detected on biopsy. Which of the following statements is FALSE regarding this condition?
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Role of TARE in HCC

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Q)Regarding the role of TARE in HCC False  statement is

a) Diagnostic angiography required
b) Portal Vein Thrombosis is a contraindication

c) Beta particle and tissue penetration is  from 2.5 to 11 mm

d) Preprocedural albumin bind technitium  scintigraphy is  required.

Gastric Lymphadenopathy

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Q ) which is one of the  criteria for diagnosis of gastric lymphadenopathy
a. mesenteric lymphoadenopathy
b. hepatic involvement

c. general lymph adenopathy
d . blood count within normal limt

Ans d

Dawson criteria

(1) absence of peripheral lymphadenopathy at the time of presentation;

(2) lack of enlarged mediastinal lymph nodes;

(3) normal total and differential white blood cell count

(4) predominance of bowel lesion at the time of laparotomy with only lymph nodes obviously affected in the immediate vicinity; and

(5) no lymphomatous involvement of liver and spleen

 

Staging Anal Cancer

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Anal Cancer Staging MCQ
Q) In anal carcinoma, involvement of the external iliac lymph nodes indicates which stage of disease according to the AJCC staging system?
a) Stage II
b) Stage IIIA
c) Stage IIIB
d) Stage IV (M1)
Correct Answer: c) Stage IIIB
Explanation: Primary tumor (T) TX: primary tumor cannot be assessed T0: no evidence of primary tumor Tis: carcinoma in situ (Bowen disease, high-grade squamous intraepithelial lesion [HSIL], anal intraepithelial neoplasia II-III [AIN II-III]) T1: tumor 2 cm or less in greatest dimension T2: tumor >2 cm but <5 cm in greatest dimension T3: tumor >5 cm in greatest dimension T4: tumor of any size invades adjacent organ(s), e.g. vagina, urethra, bladder (Note: direct invasion of the rectal wall, perirectal skin, subcutaneous tissue, or the sphincter muscle(s) is not classified as T4) Regional lymph nodes (N) Nx: regional lymph nodes cannot be assessed N0: no regional lymph node metastasis N1: metastasis in regional lymph nodes N1a: metastases in inguinal, mesorectal, and/or internal iliac lymph nodes N1b: metastases in external iliac lymph nodes N1c: metastases in external iliac and in inguinal, mesorectal, and/or internal iliac lymph nodes Distant metastasis (M) Mx: distant metastasis cannot be assessed M0: no distant metastasis M1: distant metastasis (Note: involvement of para-aortic or more distant lymph nodes is considered M1) AJCC Staging: Stage 0: Tis N0 M0 Stage I: T1 N0 M0 Stage II: T2, T3 N0 M0 Stage IIIA: T1, T2, T3 N1 M0 Stage IIIB: T4 N0/N1 OR T1, T2, T3 with N1b or N1c Stage IV: Any T, any N, M1