Q) Patient with 2cm lung nodule , biopsy proven adenocarcinoma. CT shows hilar lymph node 1.5cm and left pleural effusion. Pleural fluid cytology is positive for malignant cells. What is the stage?
a. T1N1M0
b. T1N2M1
c. T4N1M0
d. T1N1M1
Oncosurgery
Hereditary pancreatic cancers
Hereditary pancreatic cancers questions is asked many times in NEET SS and GI and onco Surgery CET
Please understand the difference between x% lifetime risk of pancreatic cancer and x fold increase in risk as compared to normal population
- PRSS & SPINK 1 - Familial pancreatitis 40% lifetime increase . 50 fold increase as compared to Normal
- STK 11 - Peutz Jeghers - 100 fold increase in Pancreatic cancer . Also associated with lung, ovarian, breast, uterine, and testicular cancers
- CFTR - cystic fibrosis - 30 fold increase
- Familial atypical mole and multiple melanoma syndrome (CDKN2A gene mutation). CDKN2A - 20 fold increase
- BRCA 2 - 10 fold increase
- Lynch Syndrome ( MLH) ( MSH) - 8 fold increase
- FAP APC gene - 4 fold
Adenoid Cystic carcinoma of Parotid
Q) 52 year old male undergoes excision of mucoepidermoid carcinoma of parotid. Resection margins are positive?
Next step
a) Re resection
b) Radiotherapy
c) Wait and watch - slow growing tumor
d) Chemotherapy
All questions on head and neck onco are here
HCC management
Q) 55 year old male with HBV, CHILD B Cirrhosis with HCC. CT shows 2 lesions 2 cm each in segment V and VI. What would be the best approach in him?
a) Right hepatectomy
b) Liver transplant
c) TACE
d) Chemotherapy
60 Questions on Liver starts here
Paget disease Breast 2
Q) Paget disease classification in TNM what is false? ( Breast Onco)
1. Paget without invasive cancer is Tis
2. Paget with DCIS is Tis
3. Paget with underlying tumor classified as per tumor
4. Involvement of skin and nipple is stage 4