Q). 45 yr old Known case of diverticular disease, presents with left lower abdominal pain , on CT sigmoid wall thickening with fat stranding. All of the following can be done except a) Admit and iv antibiotic b) Colonoscopy after resolution c) Elective colectomy after resolution d) Out patient oral antibiotic
a) It corelates with cirrhosis b)Range of sodium value is 125-137 c)It relates to vasoconstriction d) Used for allocation in DDLT patients
Ans c
MELD was originally developed to predict three-month mortality following transjugular intrahepatic portosystemic shunt (TIPS) placement and was derived using data from a population of 231 patients with cirrhosis who underwent elective TIPS placement.
Range of MELD score is 6-40
MELD Score = 10 x (0.957 x Ln(serum creatinine mg/dL) + 0.378 x Ln(serum bilirubin mg/dL) + 1.120 x Ln(INR) + 0.643 )
For candidates with an initial MELD score greater than 11, the MELD score is then re-calculated as follows: MELDNa = MELD(i) + 1.32*(137-Na) - [0.033*MELD(i)*(137-Na)]
Sodium values less than 125 mmol/L will be set to 125, and values greater than 137 mmol/L will be set to 137.
It is used for allocation in DDLT to assess wait list mortality
MELD score has also proved to be an effective predictor of outcome in other situations, such as
Patients with cirrhosis going for surgery and patients with fulminant hepatic failure or alcoholic hepatitis.
The MELD score does have limitations in situations where the INR or creatinine may be elevated due to reasons other than liver disease, and its implementation for organ allocation purposes does not take into consideration several conditions that benefit from liver transplantation.
Q) Regarding ICG clearance rate . Which is false.. a) It assess total liver function
b) Heterogenous uptake in liver may lead to false negative result c) Measures blood supply d) ICG clearance Measured non invasively via spectrophotometry
Q. 56 year ls male is diagnosed with ca rectum and multiple liver metastasis . Which of the following is not a Poor risk factor according to Fong score
a) Node + b) Disease free interval more than 1 yr c) 2 Liver Mets
d) Single metastasis 6 cm
Ans b
Fong score is for Survival after treatment for metastatic colorectal cancer to the liver. It includes 5 variables for which score is alloted to each point
Nodal status of primary
Disease-free interval from the primary to discovery of the liver metastases of <12 months