General Surgery

NEET, DNB questions from general surgery

Endocrine cells of Pancreas

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Q  Which is wrongly matched ( Free Questions) (#AIIMS 2021 GI Recall) 

a) Alpha cell - pancreatic poly peptide

b) Beta cell - insulin

c) Epsilon cell - ghrelin

d) Delta cell -  somatostatin

Ans a, ALpha cells

Alpha cells secrete glucagon

Pancreatic polypeptide is from F cells which form 15% of islet mass and are seen in Head and Uncinate process of Pancreas

Also alpha cells are the first cells to develop in the lineage
Sabiston Textbook of Surgery: The Biological Basis of Modern Surgical Practice

REf Sabiston 21st edition page 943

 

Smoking treatment

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Q) Smoking cessation- Not a  first line drug option ?

a) Clonidine 

b) Nicotine replacement (patches)

c) Varenicline

d)  Bupropion

Ans A) clonidine

NRT ,  varenicline (Chantix), and bupropion (Zyban) are the three principal firstline pharmacotherapies recommended for use either alone or in combination 

Clonidine and nortriptyline—as second-line pharmacotherapies for tobacco dependence typically used when a smoker cannot use first-line medications due to either contraindications or lack of effectiveness.

Ref Devita